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Mapping of the rat glypican genes
C Szpirer1, J Szpirer, M Rivière
1Institut de Biologie et de Médecine Moléculaires, Université Libre de Bruxelles, Rue Profs Jeener et Brachet 12, B-6041 Gosselies, Belgium. cszpirer@dbm.ulb.ac.be
Cytogenetics and Cell Genetics
|July 28, 2001
Abstract:
The glypicans compose a family of glycosylphosphatidylinositol (GPI)-anchored heparan sulfate proteoglycans that play a role in the control of cell division and growth regulation. So far, six members (GPC1-6) of this family are known in vertebrates. The rat glypican gene 3 (Gpc3) was previously assigned to chromosome Xq36 (Shen et al., 1997). Using standard and radiation cell hybrids, we localized the five other rat glypican genes.