Related Experiment Videos
Rhinosporidiosis and peripheral keratitis
S Bhomaj1, J C Das, Z Chaudhuri
1Department of Ophthalmology, Guru Nanak Eye Centre, New Delhi, India.
Abstract:
Report of a case of peripheral keratitis caused by Rhinosporidium seeberi. The patient was seen in a referral practice. Corneal scraping was performed on a middle-aged female patient presenting with peripheral keratitis and progressive nasal obstruction that revealed spores suggestive of rhinosporidiosis. The patient was started on topical amphotericin B 0.15% eye drops. Ear, nose, and throat (ENT) examination showed presence of a polypoid lesion in the left nostril for which a polypectomy was performed. Histopathological examination confirmed rhinosporidiosis. Complete resolution of the keratitis was observed. Topical amphotericin B is an effective drug in the management of this condition. Keratitis secondary to rhinosporidial infection has not been described although occasional patients with limbal and scleral involvement have been reported. Corneal scraping was effective in helping us make a tentative diagnosis.
Insights
This case report details peripheral keratitis caused by Rhinosporidium seeberi. Topical amphotericin B effectively treated the eye infection, demonstrating its utility in managing this rare condition.
Area of Science:
- Ophthalmology
- Mycology
- Infectious Diseases
Background:
- Rhinosporidiosis is a fungal infection typically affecting the nose and eyes.
- Peripheral keratitis secondary to Rhinosporidium seeberi is rare, with limited case documentation.
Observation:
- A middle-aged female presented with peripheral keratitis and nasal obstruction.
- Corneal scraping revealed spores suggestive of Rhinosporidium seeberi.
- An associated polypoid nasal lesion was identified and surgically removed.
Findings:
- Histopathology confirmed rhinosporidiosis.
- Topical amphotericin B (0.15% eye drops) led to complete resolution of keratitis.
- Corneal scraping proved effective for initial diagnosis.
Implications:
- Topical amphotericin B is a viable treatment for Rhinosporidium seeberi-induced keratitis.
- This case expands the understanding of ocular manifestations of rhinosporidiosis.
- Early diagnosis via corneal scraping is crucial for effective management.