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Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module
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Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module

Published on: June 18, 2015

Resveratrol inhibits the expression of cyclooxygenase-2 in mammary epithelial cells

K Subbaramaiah1, A J Dannenberg

  • 1Department of Medicine, New York Presbyterian Hospital, Cornell, New York 10021, USA.

Advances in Experimental Medicine and Biology
|August 2, 2001
PubMed
Abstract

No abstract available in PubMed .

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Inhibition of Cdk Activity02:34

Inhibition of Cdk Activity

The orderly progression of the cell cycle depends on the activation of Cdk protein by binding to its cyclin partner. However, the cell cycle must be restricted when undergoing abnormal changes. Most cancers correlate to the deregulated cell cycle, and since Cdks are a central component of the cell cycle, Cdk inhibitors are extensively studied to develop anticancer agents. For instance, cyclin D associates with several Cdks, such as Cdk 4/6, to form an active complex. The cyclin D-Cdk4/6 complex...

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