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Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
Published on: April 22, 2016
Biotransformation of selamectin with Streptomyces lydicus SX-1298 using a novel static agar fermentation system with
M S Pacey1, M M Barnes, R A Monday
1Veterinary Medicine Discovery, Pfizer Global Research and Development, Sandwich, Kent, UK. mike_pacey@sandwich.pfizer.com
The Journal of Antibiotics
|August 2, 2001
Abstract:
A novel approach to biotransformation is described using a solid medium matrix and Reemay mesh that gives efficient biotransformation of compounds with minimal matrices in the ensuing gum solids. Using this approach with a newly isolated biotransforming organism, Streptomyces lydicus SX1298, a series of hydroxylations and an O-demethylation is described for selamectin the first endectocide for cats and dogs.

