[Microbiological aspects of application of fluoroquinolones in surgery]

Antimicrobic activity of fluorochinolons with regard to pathogenic organisms of purulent-septic surgical infection was studied. In comparison with cephalosporins of the third generation, higher activity of fluorochinolons is noted with regard to majority aerobic microorganisms, and to pseudomonads, in particular. Optimal pharmacokinetics properties, good compliance, wide antimicrobic spectrum permits to use fluorochinolons in conduction of empirical antibacterial therapy for the infection occurrence prophylaxis in surgical practice, and for the selective intestinal decontamination, in particular.