Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quantification of the UPDRS Rigidity Scale.

S K Patrick1, A A Denington, M J Gauthier

  • 1Division of Neuroscience, University of Alberta, Edmonton, Canada. spatric@emory.edu

IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society
|August 3, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Proton Distribution Radii of ^{16-24}O: Signatures of New Shell Closures and Neutron Skin.

Physical review letters·2022
Same author

Two-Neutron Halo is Unveiled in ^{29}F.

Physical review letters·2020
Same author

Evidence for a New Compact Symmetric Fission Mode in Light Thorium Isotopes.

Physical review letters·2020
Same author

Swelling of Doubly Magic ^{48}Ca Core in Ca Isotopes beyond N=28.

Physical review letters·2020
Same author

Towards the Limits of Existence of Nuclear Structure: Observation and First Spectroscopy of the Isotope ^{31}K by Measuring Its Three-Proton Decay.

Physical review letters·2019
Same author

Permutation Entropy and Signal Energy Increase the Accuracy of Neuropathic Change Detection in Needle EMG.

Computational intelligence and neuroscience·2018
Same journal

Transfer Learning with Simulated and Recorded Data Improves Predictions of Lateral Pinch Thumb-Tip Forces.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2026
Same journal

Sensing Muscle Deformation for Upper-Limb Prosthetic Control: a Narrative Review.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2026
Same journal

Entropy-Based Graph Learning Framework for Cross-Subject Detection of Electrical Status Epilepticus During Sleep (ESES).

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2026
Same journal

Touch-related electrophysiology activity promotes human movements initiation.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2026
Same journal

Ultrasound-Informed State Estimation of Wrist Tremor Dynamics via Koopman Operator for Personalized Sensory Peripheral Nerve Stimulation.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2026
Same journal

Motion Intention Recognition and DDPG-Based Adaptive Impedance Control for a Robotic Upper-Limb Exoskeleton.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2026
See all related articles

This study introduces a device to objectively measure parkinsonian rigidity. Its mechanical impedance measurements show reliability comparable to clinical scales, offering a more sensitive tool for Parkinson's disease assessment.

Area of Science:

  • Neurology
  • Biomedical Engineering
  • Movement Disorders

Background:

  • Parkinsonian rigidity is clinically assessed using subjective scales like the Unified Parkinson's Disease Rating System (UPDRS).
  • These subjective scales face challenges with sensitivity and reliability in accurately quantifying rigidity.
  • Objective quantification methods are needed to improve the assessment of Parkinson's disease motor symptoms.

Purpose of the Study:

  • To evaluate the reliability and validity of a novel device for quantifying parkinsonian rigidity at the elbow and wrist.
  • To compare the device's objective measurements with traditional clinical rating scales.
  • To establish a relationship between objective mechanical impedance and subjective UPDRS rigidity scores.

Main Methods:

  • A device with small sensors was used to measure forces and angular displacements during passive limb movement.

Related Experiment Videos

  • Mechanical impedance, encompassing elastic and viscous stiffness, was calculated from sensor data.
  • Interexaminer agreement was assessed for both the device's measures and UPDRS scores in Parkinson's disease patients.

    • Main Results:

    • The device demonstrated reliable quantification of parkinsonian rigidity.
    • Interexaminer agreement for mechanical impedance measurements was comparable to UPDRS clinical scores.
    • UPDRS ratings were found to be potentially overestimated during reinforcement maneuvers.
    • A nonlinear relationship was identified between mechanical impedance and UPDRS rigidity ratings.

    Conclusions:

    • The developed device offers a reliable and valid method for objectively quantifying parkinsonian rigidity.
    • Mechanical impedance measurements provide an objective correlate to subjective clinical rigidity assessments.
    • This technology has the potential to enhance the sensitivity and reliability of Parkinson's disease motor assessments.