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Late-onset GM2 gangliosidosis presenting as burning dysesthesias
G C Chow1, J T Clarke, B L Banwell
1Division of Neurology, University of Toronto and The Hospital for Sick Children, Toronto, Ontario, Canada.
Pediatric Neurology
|August 3, 2001
Abstract:
Two brothers with a painful neuropathy as a component of late-onset GM2 gangliosidosis of the Sandhoff type are presented. A dramatic response of the severe dysesthesias to amitriptyline and gabapentin is described. Symptomatic sensory neuropathy may be a component of late-onset GM2 gangliosidosis.