Related Experiment Videos
[Treatment of vasculitis with antineutrophil cytoplasmic autoantibodies (ACPN)]
1Service de Néphrologie-Immunologie clinique, Hôtel-Dieu, 30, bd Jean Monnet, F44093 Nantes. vesnault@nantes.inserm.fr
Presse Medicale (Paris, France : 1983)
|August 4, 2001
Abstract:
DIAGNOSIS OF RENAL INVOLVEMENT: The diagnosis of renal involvement in patients with Wegener's disease and microscopic polyangeitis is facilitated with the search for antineutrophil cytoplasmic autoantibodies (ANCA) but still requires biopsy for confirmation.
Two Therapeutic Phases:
Induction should be initiated immediately, and generally leads to initial remission. Long-term treatment is then needed to reduce the risk of recurrence and relapse.
Follow-Up:
Close monitoring of ANCA levels is important in these patients. Several protocols are currently under evaluation with the aim of limiting immunosuppression toxicity.