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Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

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Meningeal inflammatory pseudotumour: a case report.

L Gollogly¹, B Sadzot, J P Lejeune

¹Laboratory of Neuropathology, University Hospital of Liège, Belgium.

Acta Neurologica Belgica

|August 7, 2001

Summary

A rare meningeal inflammatory pseudotumor in a young male caused focal seizures and headaches. Successful surgical removal and steroid treatment led to a full recovery with no recurrence at 3 years.

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Area of Science:

Neurology
Pathology
Immunology

Background:

Meningeal inflammatory pseudotumors are rare intracranial lesions.
Differentiating these from malignant tumors is crucial for appropriate management.

Observation:

A 23-year-old male presented with focal seizures and headaches.
Brain imaging revealed a 3.5 cm left parietal meningeal mass.

Findings:

Histopathology confirmed a dense lymphoid infiltrate, predominantly polyclonal B cells.
Cultures and serological tests were negative for infection or systemic autoimmune disease.
Postoperative brain edema resolved with steroid therapy.

Implications:

This case highlights the importance of considering inflammatory pseudotumors in the differential diagnosis of meningeal masses.
Complete resection and appropriate medical management can lead to favorable long-term outcomes.
Further research into the pathogenesis and classification of intracranial inflammatory pseudotumors is warranted.