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Concomitant angioimmunoblastic T-cell lymphoma and low grade B-cell lymphoproliferative disorder
C Christopoulos1, A Tassidou, S Golfinopoulou
1Second Department of Internal Medicine, Thriasio General Hospital, Athens, Greece. chrada@ath.forthnet.gr
Clinical and Laboratory Haematology
|August 8, 2001
Abstract:
The presence of a rearranged immunoglobulin gene, in addition to the expected T-cell receptor gene rearrangement, is a frequent, albeit poorly understood, finding in the setting of angioimmunoblastic lymphadenopathy. A case of an angioimmunoblastic T-cell lymphoma is presented, where this apparently paradoxical dual gene rearrangement could be ascribed to the coexistence of an occult B-cell lymphoproliferative disorder.