[Allergy to penicillin: facts and controversies]

Correct diagnosis in patients with side effect during benzylpenicillin (penicillin G) treatment is highly problematic. It is accepted, that hypersensitivity to penicillin is overdiagnosed. Very little qualitative information is available on the diagnostic and differentiation of penicillin allergy. On present stage it is not techniques permitting to exclude anaphylaxis. This paper describe topical knowledge about risks administration of benzylpenicillin to patients suspected of penicillin hypersensitivity. Precious advice in diagnostic procedures and therapeutic management was given.