[Influence of hyperbaric oxygenation on clinico-immunologic indices in children with acute diffuse peritonitis]

Area of Science:

• Pediatric Surgery
• Immunology
• Hyperbaric Medicine

Context:

• Acute diffuse peritonitis of appendicular genesis is a severe condition in children.
• This condition is often accompanied by a moderate immunodepressive state.
• Complex treatment strategies are essential for managing pediatric peritonitis.

Purpose:

• To investigate the impact of hyperbaric oxygenation (HBO) on clinical-immunologic indexes.
• To evaluate the efficacy of HBO as part of complex treatment for pediatric appendiceal peritonitis.
• To assess HBO's role in modulating the immune status during this disease.

Summary:

• The study examined the effects of hyperbaric oxygenation (HBO) on clinical and immunological markers in children undergoing complex treatment for acute diffuse peritonitis of appendicular origin.
• Results indicated that HBO application was effective in improving the measured indexes.
• Specifically, HBO demonstrated positive effects in patients presenting with a moderate immunodepressive state.

Impact:

• Hyperbaric oxygenation (HBO) can be a valuable adjunct therapy in pediatric appendiceal peritonitis.
• HBO may help restore immune function in children with peritonitis.
• This approach offers potential for improved patient outcomes in complex surgical cases.