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[Autologous blood transfusion].

N Rosencher1, C Conseiller

  • 1Service d'anesthésie-réanimation Hôpital Cochin 75679 Paris.

La Revue Du Praticien
|August 16, 2001
PubMed
Summary
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Autologous blood transfusion reduces exposure to donor blood, with renewed interest due to potential Bovine Spongiform Encephalopathy (BSE) agent transmission. This highlights the importance of transfusion safety and alternative techniques.

Area of Science:

  • Transfusion Medicine
  • Infectious Disease Control

Context:

  • Autologous blood transfusion (ABT) is a primary method to minimize allogeneic blood exposure.
  • Historically, ABT aimed to prevent viral contamination (Hepatitis B Virus, Hepatitis C Virus, Human Immunodeficiency Virus).
  • The risk of viral transmission via allogeneic blood has significantly decreased, making the cost-effectiveness of ABT questionable for this purpose.

Purpose:

  • To re-evaluate the role of autologous blood transfusion in light of emerging concerns.
  • To explore the implications of potential Bovine Spongiform Encephalopathy (BSE) agent transmission through blood.
  • To emphasize the precautionary principle in transfusion practices.

Summary:

  • While the risk of viral transmission from allogeneic blood is now minimal, a recent study suggests a potential risk of BSE agent transmission.

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  • This finding necessitates a re-evaluation of autologous transfusion techniques.
  • The precautionary principle supports the use of alternatives to allogeneic blood when feasible.

    • Impact:

    • A renewed interest in autologous transfusion techniques is warranted.
    • This could influence public health policies regarding blood transfusion safety.
    • Further research is needed to confirm or refute the potential transmission of the BSE agent via blood.