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Updated: Aug 14, 2026
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Published on: May 4, 2022
[Surgery for non-small cell lung cancer based on the T factor]
1Department of Thoracic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
Nihon Geka Gakkai Zasshi
|August 17, 2001
Summary
Surgery for non-small cell lung cancer (NSCLC) is complex. While limited surgery may preserve lung function, complete resection offers better long-term survival for advanced cases without N2 disease.
Area of Science:
- Oncology
- Thoracic Surgery
- Pulmonary Medicine
Context:
- Non-small cell lung cancer (NSCLC) staging relies on the T factor to guide treatment decisions.
- Surgical indications vary based on tumor characteristics like size, location, invasion, and metastasis.
- Limited surgery in early-stage NSCLC may preserve pulmonary function but carries a higher recurrence risk.
Purpose:
- To review surgical indications for non-small cell lung cancer (NSCLC) based on the T factor.
- To analyze the outcomes of limited versus complete resection in NSCLC patients.
- To identify criteria for selecting patients who may benefit from surgical intervention.
Summary:
- Peripheral, small NSCLC patients undergoing limited surgery show preserved lung function but reduced long-term survival due to recurrence.
- Complete resection in locally advanced NSCLC with specific T3/T4 invasions and metastasis can lead to long-term survival.
- Surgery is recommended for NSCLC patients without N2 disease, considering tumor invasion and metastasis.
Impact:
- Informing surgical decision-making for NSCLC patients based on detailed T-factor assessment.
- Highlighting the trade-offs between lung function preservation and survival outcomes in NSCLC surgery.
- Guiding future research on optimal surgical strategies for diverse NSCLC presentations.
