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Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
Published on: March 11, 2016
[Ultrasound for initial evaluation of post-traumatic renal lesions in children]
P Pietrera1, Y Badachi, A Liard
1Services de Radiologie, Chu de Rouen, rue de Germont, F-76031 ROUEN, France.
Insights
Color Doppler Ultrasound (CDUS) can effectively rule out major pediatric renal trauma when normal. However, its accuracy is reduced by urinomas, and imaging strategy should not depend on hematuria type.
Area of Science:
- Pediatric Radiology
- Medical Imaging
- Trauma Surgery
Background:
- Pediatric renal trauma evaluation requires accurate imaging.
- Color Doppler Ultrasound (CDUS) and enhanced Computed Tomography (CT) are used.
- Determining optimal first-line imaging is crucial.
Purpose of the Study:
- Compare CDUS findings and limitations to enhanced CT in pediatric renal trauma.
- Identify indications for initial imaging workup in pediatric renal trauma.
Main Methods:
- Retrospective review of 17 pediatric patients (3-18 years) with renal trauma.
- All patients had hematuria.
- 16 patients underwent both CDUS and enhanced CT (gold standard).
Main Results:
- No correlation found between hematuria severity and lesion grade.
- CDUS missed fractures in 4 cases.
- CDUS misdiagnosed pedicular lesions in 3 cases with uro-hematoma.
Conclusions:
- Imaging strategy should not be based on hematuria type.
- Urinomas negatively impact CDUS sensitivity.
- A normal CDUS may suffice to exclude major renal injury if performed under ideal conditions.
Purpose:
To describe the findings and limitations of color doppler ultrasound (CDUS) compared to enhanced CT in the evaluation of pediatric renal trauma and to determine the indications for first line imaging work up.
Patients And Methods:
17 children (9 girls) aged 3 to 18 years were shown to have one or multiple post-traumatic renal lesions. All renal lesions were unilateral. All children presented with hematuria (microscopic (n=8), gross (n=7), not specified (n=2)). 16 had CDUS and enhanced CT (gold standard). A 13-year old girl had been imaged by both CDUS and IVU.
Results:
No correlation between the degree of hematuria and the severity of renal lesion could be found. Final diagnosis was: fracture with uro-hematoma (n=6), contusion (n=5), pedicular lesion (n=2), clotted ureter (n=1), intra cystic hemorrhage (n=1), subcapsular hematoma (n=1), urinoma with no evidence of fracture (n=1), extra-urinary lesion (n=7). In four cases, CDUS was abnormal but the diagnosis of fracture had not been made. In 3 cases, a uro-hematoma was present and CDUS misdiagnosed a pedicular lesion.
Conclusion:
Imaging strategy should not rely on the type of hematuria. Presence of a urinoma alters the sensitivity of CDUS. When performed in ideal conditions, a comprehensive normal CDUS examination is probably sufficient to exclude a major renal injury.
Related Concept Videos
Imaging Studies I: Kidney, Ureter, and Bladder Studies
Imaging Studies II: Ultrasonography
Imaging Studies III: Computed Tomography
Imaging Studies IV: Magnetic Resonance Imaging
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Acute Kidney Injury IV: Diagnostic Studies and Prevention

