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Diffuse liver lesions among the general population of western Siberia
S A Kurilovich1, O V Reshetnikov, A N Rybiakov
1Institute of Internal Medicine, Novosibirsk, Russia. ksa@itr.nsu.ru
International Journal of Circumpolar Health
|August 18, 2001
Abstract:
The study was aimed at ascertaining the prevalence of diffuse liver lesions and associated factors in the general population of Novosibirsk, Western Siberia. A representative sample of 362 men and 870 women aged 25-64 years was investigated using ultrasound examination and blood tests for liver-derived enzymes (AST, ALT, GGT). Diffuse liver lesions (DLL) were detected in 42.8% of males and 18.7% of females. A significant association was found between DLL and elevated levels of liver enzymes. In conclusion, the prevalence of chronic liver disease is relatively frequent in the unselected urban population.