Related Experiment Video

Updated: Aug 15, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

Non Candida albicans fungal peritonitis in continuous ambulatory peritoneal dialysis patients

M A Kleinpeter1, A A Butt

  • 1Tulane University Health Sciences Center, Section of Nephrology, New Orleans, Louisiana, USA.

Advances in Peritoneal Dialysis. Conference on Peritoneal Dialysis
|August 21, 2001
PubMed

Insights

Non-Candida albicans peritonitis (NCAP) in continuous ambulatory peritoneal dialysis (CAPD) patients often leads to catheter loss. Treatment requires antifungal agents and peritoneal dialysis catheter removal for better outcomes.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Mycology

Background:

  • Continuous ambulatory peritoneal dialysis (CAPD) is a common treatment for end-stage renal disease.
  • Peritonitis is a serious complication of CAPD, with Candida species being a potential cause.
  • Non-Candida albicans peritonitis (NCAP) presents unique challenges in management.

Observation:

  • Four episodes of NCAP occurred in three CAPD patients.
  • Identified risk factors included diabetes mellitus and prior antibiotic use for exit-site infection or peritonitis.
  • Patients received antifungal therapy with fluconazole or amphotericin B.

Findings:

  • All NCAP cases resulted in eventual peritoneal dialysis catheter loss.
  • One patient experienced catheter loss six months after initial salvage due to refractory Candida (Torulopsis) glabrata peritonitis.
  • Standard antifungal treatments showed limited success, highlighting treatment complexities.

Implications:

  • This study suggests that NCAP management in CAPD patients necessitates peritoneal dialysis catheter removal.
  • Aggressive antifungal therapy in conjunction with catheter removal may improve patient outcomes.
  • Further research is needed to establish optimal treatment protocols for NCAP in CAPD.

More Related Videos

A Periprosthetic Joint Candida albicans Infection Model in Mouse04:37

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

A Catheter-Related Candida albicans Infection Model in Mouse03:24

A Catheter-Related Candida albicans Infection Model in Mouse

Published on: March 22, 2024

Related Concept Videos

Peritoneal Dialysis I: Introduction and Procedure01:30

Peritoneal Dialysis I: Introduction and Procedure

Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...