[Tissue hypoxia in acute myocardial infarction and possible approaches to its correction]

Gas exchange values were studied in 94 patients with complicated myocardial infarction. The degree of hypoxia correlated with the severity of complications during the acute stage of disease, which coincided with disorders in the myocardial contractile function. Hyperbaric oxygenation (HBO) in a sparing regimen, added to combined therapy of acute myocardial infarction, effectively liquidated tissue hypoxia and improved the contractile and pumping function of the heart. HBO in combination with antioxidants is the most effective in acute myocardial infarction after essential decrease of paO2 and pa-vO2 during the early postinfarction period in patients with signs of heart dilatation and decreased contractility; in addition, the efficiency of the method depends on the pattern of the preinfarction period.