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Plants with central analgesic activity.

R N Almeida1, D S Navarro, J M Barbosa-Filho

  • 1Laborat6rio de Tecnologia Farmacêutica, Universidade Federal da Paraíba, João Pessoa, Brazil. reinaldo@ltf.ufpb.br

Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
|August 23, 2001
PubMed
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This review explores global plant analgesic activities, focusing on species from Brazil that affect the central nervous system. It details 166 plants from 79 families with pain-relieving properties.

Area of Science:

  • Ethnobotany
  • Pharmacology
  • Natural Products Chemistry

Background:

  • Plants have a long history of use in traditional medicine for pain relief.
  • Understanding plant-based analgesics is crucial for developing new pain management strategies.
  • The central nervous system (CNS) is a key target for analgesic compounds.

Purpose of the Study:

  • To conduct a comprehensive global review of plants with analgesic activity.
  • To highlight plant species, particularly those from Brazil, with CNS-acting analgesic properties.
  • To document the diversity of plant families exhibiting analgesic potential.

Main Methods:

  • Literature review of scientific databases and ethnobotanical records.
  • Systematic compilation of plant species reported to have analgesic effects.

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  • Classification of plants based on geographical origin and mechanism of action (CNS-acting).

    • Main Results:

    • A total of 166 plant species were identified with reported analgesic activity.
    • These plants belong to 79 distinct botanical families.
    • Emphasis was placed on species found globally, with specific attention to those from Brazil impacting the central nervous system.

    Conclusions:

    • A significant number of plant species worldwide possess analgesic properties.
    • Ethnobotanical knowledge highlights numerous CNS-acting analgesic plants, especially in Brazil.
    • Further research into these plants could yield novel therapeutic agents for pain management.