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Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
Published on: May 16, 2014
[Iodine deficiency in the Russian Federation]
Vestnik Rossiiskoi Akademii Meditsinskikh Nauk
|August 24, 2001
Summary
Iodine deficiency (ID) surveys in Russia revealed lower iodine levels in rural areas and East Russia, correlating with increased goiter and hypothyroidism. Dietary iodine intake was below recommended levels, prompting the testing of preventive measures.
Area of Science:
- Endocrinology
- Public Health
- Epidemiology
Background:
- Iodine deficiency (ID) poses significant public health challenges, particularly in developing regions.
- Assessing ID prevalence and severity requires standardized methods and indicators.
Purpose of the Study:
- To conduct epidemiological surveys on iodine deficiency in Russia between 1992-1999.
- To evaluate the prevalence and severity of ID and related conditions like goiter, hypothyroidism, and endemic cretinism.
- To analyze dietary and water iodine intake and test preventive strategies.
Main Methods:
- Epidemiological surveys conducted in 30 Russian regions from 1992 to 1999.
- Examination of 40,999 individuals aged 7-17 years.
- Application of WHO standards for estimating ID prevalence and severity.
Main Results:
- Lower iodine concentrations were observed in rural dwellers compared to urban populations in Central Russia.
- ID was more pronounced in East Russia, with some areas experiencing severe deficiency (median 16-20 µg/l).
- Goiter prevalence was higher in rural children and East Russia, with some discrepancies between ID levels and goiter incidence.
Conclusions:
- Dietary and water iodine intake in most Russian regions was below recommended levels.
- Increased ID severity correlated with higher incidences of goiter, hypothyroidism, and endemic cretinism.
- Preventive measures using iodinated foodstuffs and medicaments were tested to combat ID-related diseases.
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