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Localized ridge augmentation using GBR and platelet-rich plasma: case reports
R Shanaman1, M R Filstein, M J Danesh-Meyer
1Department of Periodontology, Temple University, School of Dentistry, Philadelphia, Pennsylvania, USA.
Summary
Platelet-rich plasma (PRP) combined with bone allograft aided alveolar ridge regeneration for dental implants. However, PRP did not significantly improve new bone formation compared to studies without it.
Area of Science:
- Oral and Maxillofacial Surgery
- Regenerative Medicine
- Biomaterials Science
Background:
- Alveolar ridge defects often require bone augmentation for dental implant placement.
- Platelet-rich plasma (PRP) is explored for enhancing bone regeneration.
- Combining PRP with bone allografts is a potential strategy for complex defects.
Observation:
- This case series evaluated PRP combined with bone allograft for vertical and horizontal alveolar ridge augmentation.
- Augmentation procedures led to significant clinical and radiographic bone gains.
- Histological analysis confirmed new bone formation and residual allograft particles.
Findings:
- The combination of PRP and bone allograft successfully augmented alveolar ridge defects, enabling implant placement.
- Histology showed viable bone formation within the grafted areas.
- The addition of PRP did not demonstrate a quantifiable enhancement in new bone quality or quantity compared to historical guided bone regeneration (GBR) data without PRP.
Implications:
- PRP with bone allograft can facilitate dental implant placement in augmented alveolar ridges.
- Further research is needed to elucidate the specific role and potential benefits of PRP in combination with bone allografts for bone regeneration.
- Findings suggest that current GBR techniques without PRP may yield comparable bone regeneration outcomes.