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4-Amino-5-arylpyrimidines as antiinflammatory agents

S A Lang, E Cohen

Journal of Medicinal Chemistry

|June 11, 1975

Abstract:

4-Amino-5-arylpyrimidines were synthesized by a variety of methods and have demonstrated antiinflammatory activity in the carrageenan-induced edema in the rat but displayed little activity against adjuvant-induced arthritis in rats or against uv-induced erythema in guinea pigs.

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