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The hip in Stickler syndrome.
1Warren Grant Magnuson Clinical Center, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA. Rose.Peter@Mayo.edu
Journal of Pediatric Orthopedics
|August 25, 2001
Summary
Stickler syndrome frequently causes hip abnormalities and chronic hip pain, particularly in adults. Early evaluation and screening are crucial for managing hip complications in affected children and young patients.
Area of Science:
- Orthopedics
- Genetics
- Rheumatology
Background:
- Stickler syndrome is an inherited connective tissue disorder.
- Hip abnormalities and pain are not well-documented in Stickler syndrome patients.
Purpose of the Study:
- To investigate hip abnormalities and their association with age and chronic hip pain.
- To describe the prevalence of specific hip conditions in Stickler syndrome.
Main Methods:
- Retrospective analysis of 51 patients with Stickler syndrome.
- Evaluation of hip abnormalities, age, and reported chronic hip pain.
Main Results:
- 34% of adults had hip osteoarthritis; 63% of all patients experienced chronic hip pain.
- Protrusio acetabuli (10%) and coxa valga (21%) were observed.
- Adult age and arthritis correlated with hip pain; 16% of adults had prior femoral head failure.
Conclusions:
- Hip abnormalities are common in Stickler syndrome.
- Children require hip pain evaluation; screening may aid early detection of complications.
- Adults with Stickler syndrome frequently experience hip pain and osteoarthritis.