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Mediastinal fibrosis
A M Davis1, R N Pierson, J E Loyd
1Center for Lung Research, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Seminars in Respiratory Infections
|August 25, 2001
Abstract:
Mediastinal fibrosis is the least common, but the most severe, late complication of histoplasmosis. It should be differentiated from the many other less-severe mediastinal complications of histoplasmosis, and from other causes of mediastinal fibrosis. Posthistoplasmosis mediastinal fibrosis is characterized by invasive, calcified fibrosis centered on lymph nodes, which, by definition, occludes major vessels or airways.