Transjugular renal biopsy. Our experience with 67 cases

Area of Science:

• Nephrology
• Interventional Radiology
• Pathology

Background:

• Transjugular renal biopsy (TJRB) is an emerging technique for renal tissue sampling via the transjugular route.
• It is particularly indicated for patients with clotting disorders where percutaneous biopsy is precluded.
• Limited studies have reported on larger patient experiences with TJRB.

Purpose of the Study:

• To analyze the authors' experience with transjugular renal biopsy.
• To evaluate the indications, diagnostic yield, and complications of TJRB.
• To assess the utility of TJRB in patients with contraindications for percutaneous biopsy.

Main Methods:

• A retrospective analysis of 67 patients who underwent TJRB between 1993 and 1999.
• Data collected included patient demographics, indications for biopsy, procedural details, histological findings, and complications.
• TJRB was often combined with liver biopsy or hepatic vein catheterization.

Main Results:

• Renal tissue was obtained in 79% of patients, with sufficient sample for diagnosis in 73%.
• Common indications included clotting disorders (39%) and combined kidney/liver biopsy needs (46%).
• Complication rate was 18% overall, significantly higher in patients with clotting disorders (34% vs. 7%).

Conclusions:

• TJRB is a valuable diagnostic tool for glomerulopathies, especially in patients with clotting disorders.
• The procedure facilitates diagnosis when percutaneous renal biopsy is not feasible.
• Proper technique is crucial for an acceptable risk-benefit ratio, with the procedure being well-tolerated.