Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A method for measuring dermal exposure to multifunctional acrylates.

J Surakka1, S Johnsson, G Rosén

  • 1National Institute for Working Life, S-112 79 Stockholm, Sweden. Jouni.Surakka@niwl.se

Journal of Environmental Monitoring : JEM
|September 1, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tracking and Assessing Oil Spill Toxicity to Aquatic Organisms: A Novel Approach.

Environmental toxicology and chemistry·2021
Same author

Evaluating the efficacy of DGT to quantify copper in stormwater at end-of-pipe.

Chemosphere·2019
Same author

Public Response to Suicide News Reports as Reflected in Computerized Text Analysis of Online Reader Comments.

Archives of suicide research : official journal of the International Academy for Suicide Research·2019
Same author

Response to anti-PD1 therapy with nivolumab in metastatic sarcomas.

Clinical sarcoma research·2017
Same author

Palliative CT-Guided Cordotomy for Medically Intractable Pain in Patients with Cancer.

AJNR. American journal of neuroradiology·2016
Same author

Progress in the treatment of Ewing sarcoma: are the rumors of the demise of cytotoxic chemotherapy premature?

Klinische Padiatrie·2015

A new tape-stripping method effectively measures dermal exposure to tripropylene glycol diacrylate (TPGDA), a common furniture coating allergen. This efficient, accurate, and economical technique aids in assessing occupational risks from multifunctional acrylates.

Area of Science:

  • Occupational Health and Safety
  • Dermal Toxicology
  • Analytical Chemistry

Background:

  • UV-curable acrylates, like tripropylene glycol diacrylate (TPGDA), are widely used in furniture coatings.
  • TPGDA is a known skin allergen and irritant, necessitating robust exposure assessment methods.
  • Current methods for measuring dermal exposure to such compounds are insufficient.

Purpose of the Study:

  • To develop and validate a skin and surface sampling method for assessing occupational dermal exposure to multifunctional acrylates.
  • To establish a quantitative gas chromatographic analysis method for TPGDA.
  • To identify the most effective tape for sampling TPGDA from skin and surfaces.

Main Methods:

  • Tape stripping technique was employed using twelve different adhesives to sample TPGDA and UV-coating from glass, guinea pig skin, and human volunteer skin.

Related Experiment Videos

  • Optimization of variables including applied dose, retention time, tape adhesion time, and number of strippings.
  • Gas chromatography was used for quantitative analysis of collected samples.

    • Main Results:

    • Fixomull tape demonstrated superior performance in sampling and analysis, showing consistent removal efficiencies.
    • Average removal efficiency for TPGDA from exposed skin was 85% (RSD = 14.1) with a single stripping.
    • Average removal efficiency for UV-resin was 63% (RSD = 20.2) with a single stripping.

    Conclusions:

    • The developed tape-stripping and gas chromatographic method is efficient, accurate, and economical for measuring dermal exposure to multifunctional acrylates.
    • This method provides a sensitive tool for assessing occupational skin exposure to acrylates and other surface contaminants.
    • The findings support improved safety protocols in industries utilizing UV-curable coatings.