Related Experiment Video
Updated: Aug 18, 2026

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
Published on: September 22, 2017
[Clinical evaluation of the Heidelberg Retina Tomograph II]
H Uchida1, G Tomita, Y Kitazawa
1Department of Ophthalmology, Gifu University School of Medicine, 40 Tsukasa-machi, Gifu 500-8705, Japan.
Purpose:
To evaluate the usefulness of Heidelberg Retina Tomograph (HRT) II prototype, which is an easily handled model for routine optic disc examination in glaucoma clinics.
Methods:
Ten eyes of 10 normal volunteers and 18 eyes of 18 open-angle glaucoma patients followed at Gifu University were studied. The reproducibility of three consecutive optic disc measurements with a 15 degrees x 15 degrees field using HRT II and with a 10 degrees x 10 degrees field using HRT (version 2.01) were evaluated by the same examiner on the same day. We also examined the correlation of the main topographic parameters (disc area, cup area, cup/disc area ratio, rim area, cup volume, rim volume, cup shape measure) between HRT II and HRT.
Results:
The mean (+/- standard deviation) reproducibility of optic disc measurements with HRT II and HRT were 17.5 +/- 7.6 microns and 19.3 +/- 9.6 microns, respectively. This difference was not significant. All topographic parameters obtained from HRT II and HRT (R = 0.86-0.98, p < 0.01) showed statistically significant correlations with each other.
Conclusion:
The HRT II has high reproducibility of measurements and reliable stereometric parameters comparable to the conventional HRT.

