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Published on: February 28, 2019
Ovarian endodermal sinus tumor in a postmenopausal woman
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Temple University School of Medicine, 3401 N. Broad Street, Philadelphia, Pennsylvania 19140, USA.
Gynecologic Oncology
|September 5, 2001
Summary
Ovarian endodermal sinus tumors are exceptionally rare in postmenopausal women. This report details the case of a 75-year-old patient, likely the oldest documented, highlighting potential differences in tumor origin in older individuals.
Area of Science:
- Gynecologic Oncology
- Pathology
- Geriatric Medicine
Background:
- Ovarian endodermal sinus tumors (ESTs) are rare germ cell neoplasms.
- These tumors predominantly affect young women and are seldom diagnosed in postmenopausal populations.
Purpose of the Study:
- To present a rare case of ovarian endodermal sinus tumor in an elderly patient.
- To discuss the potential implications for understanding the histogenesis of ovarian ESTs in older individuals.
Main Methods:
- Case report of a 75-year-old woman diagnosed with a pure ovarian endodermal sinus tumor.
- Review of relevant literature regarding late-onset ovarian germ cell tumors.
Main Results:
- The patient presented with a pure endodermal sinus tumor of the ovary.
- This represents the oldest reported case of an ovarian endodermal sinus tumor in the medical literature.
Conclusions:
- The occurrence of ovarian endodermal sinus tumors in postmenopausal women is exceedingly rare.
- The histogenesis of ovarian endodermal sinus tumors in elderly patients may differ from that observed in younger populations, warranting further investigation.

