Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tics and its disorders.

D Marcus1, R Kurlan

  • 1Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642-8673, USA.

Neurologic Clinics
|September 5, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Design of a Multisite Study Assessing the Impact of Tic Disorders on Individuals, Families, and Communities.

Pediatric neurology·2017
Same author

Groundwater shapes sediment biogeochemistry and microbial diversity in a submerged Great Lake sinkhole.

Geobiology·2016
Same author

The molecular organization of nerve membranes : VI. The separation of axolemma from schwann cell membranes of giant and retinal squid axons by density gradient centrifugation.

The Journal of membrane biology·2013
Same author

Genome-wide association study of Tourette's syndrome.

Molecular psychiatry·2012
Same author

A randomized, double-blind, placebo-controlled trial of antidepressants in Parkinson disease.

Neurology·2012
Same author

The Human Connectome Project: a data acquisition perspective.

NeuroImage·2012
Same journal

Sports Neurology.

Neurologic clinics·2026
Same journal

Sports-Related Peripheral Nerve Injuries.

Neurologic clinics·2026
Same journal

Active Rehabilitation and Return to Play in Sports-Related Concussion.

Neurologic clinics·2026
Same journal

Autonomic Assessment and Management in Sports-Related Concussion.

Neurologic clinics·2026
Same journal

Management of Vestibular Symptoms in Sports-Related Concussion.

Neurologic clinics·2026
Same journal

Neuropsychological Assessment in Sport-Related Concussion: Evidence, Controversies, and Clinical Applications.

Neurologic clinics·2026
See all related articles

Tourette syndrome (TS), a childhood neuropsychiatric disorder, is now understood to be more common and less debilitating than previously thought. Research suggests a broader spectrum of symptoms beyond tics, potentially including OCD and ADHD.

Area of Science:

  • Neuroscience
  • Genetics
  • Psychiatry

Background:

  • Tourette syndrome (TS) is a familial neuropsychiatric disorder presenting with motor and phonic tics in childhood.
  • Historically viewed as rare and debilitating, recent research indicates TS and related tic disorders are more prevalent and less severe for most individuals.
  • Emerging evidence suggests a spectrum of TS symptomatology extending beyond tics to include conditions like obsessive-compulsive disorder (OCD), attention deficit hyperactivity disorder (ADHD), and mood disorders.

Purpose of the Study:

  • To provide a comprehensive overview of Tourette syndrome.
  • To highlight recent advancements in understanding TS classification, causes, prevalence, genetics, brain mechanisms, and treatment.
  • To discuss the differential diagnosis of Tourette syndrome.

Main Methods:

Related Experiment Videos

  • Review of current scientific literature on Tourette syndrome.
  • Analysis of new developments in TS classification and epidemiology.
  • Examination of genetic and pathophysiological findings.
  • Synthesis of updated clinical management strategies.

Main Results:

  • Tourette syndrome is more common and less debilitating than previously assumed.
  • TS symptomatology exists on a spectrum, potentially encompassing OCD, ADHD, and mood disorders.
  • Significant progress has been made in understanding the etiology, genetics, and pathophysiology of TS.

Conclusions:

  • Tourette syndrome is a complex neuropsychiatric disorder with a broader clinical spectrum than traditionally recognized.
  • Continued research into genetics, pathophysiology, and clinical management is crucial for improving patient outcomes.
  • A revised understanding of TS prevalence and symptom spectrum impacts diagnosis and treatment approaches.