Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Familial resemblance in fatness and fat distribution.

Peter T. Katzmarzyk1, Robert M. Malina, Louis Pérusse

  • 1Department of Kinesiology and Health Science, York University, North York, Ontario, Canada.

American Journal of Human Biology : the Official Journal of the Human Biology Council
|September 5, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization and response to exercise training of HDL-specific phospholipid efflux.

Journal of lipid research·2026
Same author

N-Palmitoyl Glutamine Is a Candidate Mediator of Cardiorespiratory Fitness.

Circulation·2025
Same author

Variation in cycling exercise mechanical efficiency in the HERITAGE Family Study.

Physiological reports·2025
Same author

Association of the HDL lipidome with HDL traits before and after exercise training: HERITAGE family study.

Metabolomics : Official journal of the Metabolomic Society·2025
Same author

Polygenic prediction of body mass index and obesity through the life course and across ancestries.

Nature medicine·2025
Same author

Mechanical efficiency: associations with body composition and glycemic profile in healthy adults.

European journal of applied physiology·2024
Same journal

Correction to "Background, Rationale, and Methodological Overview of the REACT Project-Return-To-Action on Growth, Motor Development, and Health After the COVID-19 Pandemic in Primary School Children".

American journal of human biology : the official journal of the Human Biology Council·2026
Same journal

Connectedness to Nature, Ceremonial Participation, and Mental and Physical Health Among Rural and Urban Wixárika in Jalisco, Mexico.

American journal of human biology : the official journal of the Human Biology Council·2026
Same journal

Relationships Between Estradiol Levels and Vaginal Lactobacillus Abundance Across the Menstrual Cycles in Women.

American journal of human biology : the official journal of the Human Biology Council·2026
Same journal

Dam-Induced Displacement and Disruption Are Associated With Salivary Cortisol Concentration and Patterns of Diurnal Variation.

American journal of human biology : the official journal of the Human Biology Council·2026
Same journal

Ethnic Variability in Anthropometric Trajectories Across the Lifespan: Findings From a Nationwide Survey in Peru.

American journal of human biology : the official journal of the Human Biology Council·2026
Same journal

Longitudinal Changes and Correlates of 24-Hour Movement Behaviors in Brazilian Older Adults.

American journal of human biology : the official journal of the Human Biology Council·2026
See all related articles

Familial resemblance for body fatness and fat distribution is significant, with heritability estimates suggesting a stronger genetic influence on overall fatness than distribution. Genes play a role in these traits within families.

Area of Science:

  • Human Biology
  • Genetics
  • Anthropometry

Background:

  • Understanding the familial aggregation of anthropometric traits is crucial for public health.
  • Previous research suggests genetic and environmental factors influence body composition.

Purpose of the Study:

  • To quantify familial resemblance in anthropometric indicators of body fatness and fat distribution.
  • To investigate the heritability of fatness and fat distribution traits.

Main Methods:

  • Analysis of 327 Caucasian participants from 102 nuclear families.
  • Measurement of fatness indicators: Body Mass Index (BMI), sum of six skinfolds (SF6), and waist circumference (WAIST).
  • Measurement of fat distribution indicators: BMI-adjusted waist circumference (WAIST(ADJ)), trunk-to-extremity skinfold ratio (TER(ADJ)), and principal component of skinfolds (PC1).

Related Experiment Videos

  • Application of a general familial correlation model to assess resemblance.

    • Main Results:

    • Significant familial resemblance was found for both fatness and fat distribution traits.
    • Heritability estimates for fatness ranged from 46-60%, and for fat distribution from 29-48%.
    • Sibling and parent-offspring correlations were significant for fatness indicators, but only sibling correlations were significant for some fat distribution indicators.
    • No spousal resemblance was observed for BMI-adjusted waist circumference, but was significant for other fat distribution measures.

    Conclusions:

    • Genetic factors contribute significantly to both fatness and fat distribution.
    • Heritability of fatness appears greater than that of fat distribution.
    • The pattern of correlations suggests a substantial role for genetic inheritance in these traits.