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Updated: Oct 4, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
[Compensatory responses in lymph nodes following by prenatal indomethacin exposure]
1Department oh Human Anatomy, I.I. Mechnikov Medical Academy of St. Petersburg.
Abstract:
Retardation of development of the structures of mesenteric lymph nodes (maximum at first 1-2 wks) was discovered in rats treated with indometacin. It was dependent on the doze of preparations. Mast cells and eosinophilic reactions associated with normalization of the stroma structure and functional activity of lymph nodes nerve structures took place in the lymph node substance as adaptive processes on the background of lymphocytopenia and incomplete development of the lymph node B zone by weeks 2-3.
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