Related Experiment Video
Updated: Oct 4, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
Published on: June 13, 2018
[Pathohistological characteristics of dermatophytic onychomycosis]
Iu G Parkhomenko1, N N Potekaev, N S Potekaev
1Research Institute of Human Morphology, 117048, Moscow.
Abstract:
A pathohistological study was made of the tissues taken from the distal phalanx of the great toe of 30 dead bodies with clinical picture of mycotic infection of nail plates. Onychomycosis was confirmed by the presence of pathogenic fungal myceliem detected microscopically. It is established that the fungus, in total onychomycosis, penetrates from the nail plate into the skin epidermis, connective tissue, bone and into the bone marrow of the phalanx. Cyst formation was found deep in the prickle-cell layer. Inflammation was rather weak reflecting a weak reactive response to the fungus presence.
Related Concept Videos
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Fungal Phylum Microsporidia
The Skin Microbiota
Candidiasis
Fungal Group Zygomycota
Fungal Phylum Basidiomycota
