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Structure-activity relationship studies of isoquinolinone type anticancer agent
1College of Pharmacy, Chonnam National University, Kwangju, Korea. shcheon@chonnam.ac.kr
Archives of Pharmacal Research
|September 6, 2001
Abstract:
Substituted isoquinolin-1-ones (1) were synthesized to test their in vitro anticancer activity. 3-Biphenyl-N-methylisoquinolin-1-one (7) showed the most potent anticancer activity against five different human cancer cell lines.