Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Track structure in biological models.

S B Curtis1

  • 1Lawrence Berkeley Laboratory, Division of Biology and Medicine, University of California 94720, USA.

Advances in Space Research : the Official Journal of the Committee on Space Research (COSPAR)
|January 1, 1986
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From mechanisms to risk estimation--bridging the chasm.

Advances in space research : the official journal of the Committee on Space Research (COSPAR)·2005
Same author

A new perspective of carcinogenesis from protracted high-LET radiation arises from the two-stage clonal expansion model.

Advances in space research : the official journal of the Committee on Space Research (COSPAR)·2003
Same author

The role of promotion in carcinogenesis from protracted high-LET exposure.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2002
Same author

Cosmic ray hit frequencies in critical sites in the central nervous system.

Advances in space research : the official journal of the Committee on Space Research (COSPAR)·2001
Same author

Cosmic ray hits in the central nervous system at solar maximum.

Advances in space research : the official journal of the Committee on Space Research (COSPAR)·2001
Same author

The importance of promotion in lung carcinogenesis for protracted exposures to radon and radon progeny.

Radiation research·2001
Same journal

Planetary Protection and the astrobiological exploration of Mars: Proactive steps in moving forward.

Advances in space research : the official journal of the Committee on Space Research (COSPAR)·2025
Same journal

Crop type discrimination using Geo-Stat Endmember Extraction and machine learning algorithms.

Advances in space research : the official journal of the Committee on Space Research (COSPAR)·2024
Same journal

A Hansel & Gretel breadcrumb-style dynamically deployed communication network paradigm using mesh topology for planetary subsurface exploration.

Advances in space research : the official journal of the Committee on Space Research (COSPAR)·2023
Same journal

Investigating Patterns of Air Pollution in Metropolises Using Remote Sensing and Neural Networks During the COVID-19 Pandemic.

Advances in space research : the official journal of the Committee on Space Research (COSPAR)·2023
Same journal

Editorial.

Advances in space research : the official journal of the Committee on Space Research (COSPAR)·2023
Same journal

Exploring the effect of COVID-19 pandemic lockdowns on urban cooling: A tale of three cities.

Advances in space research : the official journal of the Committee on Space Research (COSPAR)·2022
See all related articles

High-energy heavy ions (HZE particles) from galactic cosmic radiation pose risks during long space flights. Models analyzing HZE particle track structure for biological effects on cells are reviewed.

Area of Science:

  • Space biology
  • Radiation biology
  • Astrobiology

Background:

  • Galactic cosmic radiation (GCR) includes high-energy heavy ions (HZE particles) posing risks to astronauts on long space missions.
  • HZE particles are highly ionizing and can penetrate deep into biological tissues, creating complex ionization patterns known as track structure.

Purpose of the Study:

  • To review existing models of biological action on mammalian cells that incorporate HZE particle track structure.
  • To analyze how different models represent or utilize track structure information for predicting biological effects.

Main Methods:

  • Review of biological action models: Dual Radiation Action (DRA), ion-gamma kill (IGK), and lethal, potentially lethal (LPL).
  • Examination of track structure representations: proximity function (DRA), radial energy-density distribution (IGK), and inter-event distance (LPL).

Related Experiment Videos

Main Results:

  • The proximity function in DRA is useful for broader track characteristics but less so for highly localized energy depositions.
  • The IGK model uses radial energy-density distribution to characterize charged particle tracks.
  • The LPL model focuses on localized energy depositions (within ~10 nm) using inter-event distances (lambda).

Conclusions:

  • Different models employ distinct approaches to quantify HZE particle track structure for biological impact assessment.
  • The utility of track structure parameters varies depending on the model's focus on energy deposition scales.
  • Understanding these models is crucial for assessing radiation risks in space exploration.