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Dose rate and repair effects on cell damage in Earth orbit
F A Cucinotta1, J W Wilson, J L Shinn
1NASA Langley Research Center, Hampton, VA 23681, USA.
Advances in Space Research : the Official Journal of the Committee on Space Research (COSPAR)
|January 1, 1994
Abstract:
Radiobiology experiments performed in space will encounter continuous exposures to the cosmic rays and fractionated exposures to trapped protons which accumulate to several hundred dose fractions in a few weeks. Using models of track structure and cellular kinetics combined with models of the radiation environment and radiation transport, we consider calculations of damage rates for cell cultures. Analysis of the role of repair mechanisms for space exposures for the endpoints of survival and transformation is emphasized.