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Cardiovascular adaptations following detraining.

P B Raven1, X Shi

  • 1Dept. of Physiology, University of North Texas Health Science Center at Fort Worth 76107, USA.

Journal of Gravitational Physiology : a Journal of the International Society for Gravitational Physiology
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

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Endurance exercise training reduces tolerance to lower body negative pressure (LBNP) due to cardiac and reflex adaptations. Detraining, however, enhances the aortic-cardiac reflex, potentially compensating for reduced blood volume.

Area of Science:

  • Cardiovascular physiology
  • Exercise physiology
  • Autonomic nervous system function

Background:

  • Endurance exercise training (ET) alters blood pressure regulation during stress like lower body negative pressure (LBNP).
  • ET subjects show decreased LBNP tolerance linked to cardiac compliance and attenuated reflex responses.
  • Severe deconditioning (bed rest) enhances the aortic-cardiac reflex, possibly to compensate for reduced blood volume.

Purpose of the Study:

  • To investigate if reduced daily aerobic activity in healthy adults leads to moderate blood volume reduction.
  • To determine if such activity reduction up-regulates reflex blood pressure regulatory mechanisms.

Main Methods:

  • Subjects: Healthy, young adults.
  • Intervention: Generalized reduction in daily aerobic activities.
Keywords:
NASA Discipline CardiopulmonaryNASA Discipline Number 14-10NASA Program Space Physiology and CountermeasuresNon-NASA Center

Related Experiment Videos

  • Measurements: Assessed changes in total blood volume, plasma volume, and reflex blood pressure regulatory mechanisms.

    • Main Results:

    • Hypothesized moderate reduction in total blood and plasma volume.
    • Hypothesized up-regulation of reflex blood pressure regulatory mechanisms.

    Conclusions:

    • Reduced aerobic activity may lead to decreased blood volume.
    • This decrease may trigger compensatory enhancements in blood pressure regulatory reflexes.