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[Hypolipidemic and antioxidant effects of pyridyl-3-glyoxylic acid]
Kh U Sadykova1, A Kh Abdullaev
1Department of Propedeutics of Internal Disorders, First State Medical Institute, ul. Khamzy 103, Tashkent, 700047 Uzbekistan.
Eksperimental'Naia I Klinicheskaia Farmakologiia
|September 8, 2001
Abstract:
Pyridyl-3-glyoxylic acid reduced the blood cholesterol and triglycerides, normalized the lipoprotein spectrum, markedly decreased the intensity of lipid peroxidation, and increased the superoxide dismutase enzyme activity in the experimental rabbits with cholesterol atherosclerosis model. The efficacy of the compound exceeded that of nicotinic acid used as the reference compound.