Related Experiment Video
Updated: Jul 20, 2026
Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model
Published on: April 2, 2017
[The liver monooxygenase system activity in the long-term compression syndrome and treatment with benzonal in
F Kh Rakhmatullaev1, Z Z Khakimov
1Central Research Laboratory, Second State Medical Institute, ul Farobi 2, Tashkent, 700109 Uzbekistan.
Abstract:
A compression syndrome was reproduced in rats and rabbits aged one month. Efficacy of the benzonal treatment in the postcompression period was evaluated by measuring the parameters of antipyrin pharmacokinetics, hexenal sleep duration, and the level of medium-molecular-weight (MMW) peptides in the blood serum. It was established that benzonal restored the detoxicating liver function (significantly reduced in animals with the compression syndrome) and eliminated the pronounced endotoxemia manifestations.
