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Histoprotective effect of antihypoxant olifen during experimental acute pancreatitis
A D Tolstoi1, B I Dzhurko, R V Vashetko
1I. I. Dzhanelidze St. Petersburg Institute of Ambulance Service.
Bulletin of Experimental Biology and Medicine
|September 11, 2001
Abstract:
We evaluated the efficiency of perfusion with olifen in preventing oxidative stress at the early stage of acute pancreatitis. Transaortic perfusion with olifen prevented clinical and biochemical symptoms of acute pancreatitis, attenuated oxidative stress, reduced peritoneal exudation, and restricts the area of pancreatic necrosis to 6% tissue.