Related Experiment Video
Updated: Jul 31, 2026

Simultaneous EEG Monitoring During Transcranial Direct Current Stimulation
Published on: June 17, 2013
[Modulation by ultralow intensity electromagnetic fields on pharmacologic effects of psychotropic drugs]
A S Shtemberg1, A S Bazian, S N Shikhov
1National Research Center Institute of Medical and Biological Problems, Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Research Institute of Psychiatry, Russian Ministry of Public Health, Moscow.
Abstract:
The ultralow-intensity electromagnetic fields (EMF, frequency of 4200, modulated by a quasistochastic signal in the range of 20-20,000 Hz, power density of 15 microW/cm2, specific body absorption rate up to 4.5 mJ/kg) potentiated the hypnogenic effect of hexenal. The exposure to the EMF shortened the time of falling asleep induced by this drug and increased sleep duration in rats. The exposure to the EMF also potentiated haloperidol catalepsy: it decreased the drug threshold dose and increased the catalepsy duration. The EMF influence on the haloperidol effects was of a prolonged character: it was manifest in a selected suppression of the emotional excitation in the open-field test within 24 hours after the exposure.
Related Concept Videos
Neurochemical Transmission: Sites of Drug Action
Drugs Affecting Neurotransmitter Release or Uptake
Antidepressant Drugs: MAOIs and Other Agents
Pharmacodynamic Models: Linear Concentration–Effect Model
Brain Imaging
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Electroconvulsive Therapy

