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[Features of chromosome segregation in unfertilized human oocytes]
O A Vorob'eva1, M V Bogomolova
1D. O. Ott Institute of Obstetrics and Gynecology RAMN, St. Petersburg.
Tsitologiia
|September 13, 2001
Abstract:
Mechanisms of abnormal chromosomal segregation in female meiosis and factors exerting influence on unfertilized human oocytes have been analysed in vitro. The differences in results of cytological studies on the rate of aneuploidy have been reviewed. The advanced maternal age is primarily associated with disturbances in oocyte meiosis.