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Calcium and phosphorus in aged human cerebral arteries
Biological Trace Element Research
|September 14, 2001
Summary
Aging does not significantly alter calcium or phosphorus levels in cerebral arteries. However, calcium and phosphorus content showed significant relationships between the middle and posterior cerebral arteries.
Area of Science:
- Neurology
- Gerontology
- Biochemistry
Background:
- Cerebral artery composition changes with age, potentially impacting vascular health.
- Understanding age-related mineral accumulation is crucial for cerebrovascular disease research.
Purpose of the Study:
- To investigate age-related changes in calcium and phosphorus content within anterior, middle, and posterior cerebral arteries.
- To determine correlations of calcium and phosphorus levels among different cerebral artery segments.
Main Methods:
- Inductively coupled plasma-atomic emission spectrometry was used to quantify calcium and phosphorus.
- Analysis included anterior, middle, and posterior cerebral arteries from 16 human subjects (aged 52-96).
Main Results:
- No significant correlation was found between age and calcium or phosphorus content in any of the studied cerebral arteries.
- Significant positive correlations for both calcium and phosphorus were observed between the middle and posterior cerebral arteries.
Conclusions:
- Aging does not lead to significant accumulation of calcium or phosphorus in the anterior, middle, or posterior cerebral arteries.
- Inter-arterial relationships exist for calcium and phosphorus content, particularly between the middle and posterior cerebral arteries.
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