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Related Experiment Videos

Normal fMRI brain activation patterns in children performing a verb generation task.

S K Holland1, E Plante, A Weber Byars

  • 1Children's Hospital Research Foundation, University of Cincinnati, Cincinnati, Ohio, USA.

Neuroimage
|September 14, 2001
PubMed
Summary
This summary is machine-generated.

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Brain imaging in children reveals that language processing becomes more specialized in the left hemisphere as they age. This developmental shift in brain activation patterns was observed using functional magnetic resonance imaging.

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Cognitive Science

Background:

  • Limited understanding of brain-language relationships during childhood development.
  • Established knowledge of adult brain-language networks.

Purpose of the Study:

  • Investigate developmental changes in brain activation for semantic language tasks in children.
  • Examine the relationship between age and hemispheric lateralization of language function.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) at 3 Tesla.
  • Word fluency paradigm administered to 17 children (ages 7-18).
  • Analysis of brain activation patterns and hemispheric dominance.

Main Results:

Related Experiment Videos

  • Brain activation regions in children replicated adult findings.
  • A significant association between age and hemispheric lateralization was observed.
  • The degree of left hemisphere dominance for language tasks increased with age.

    • Conclusions:

    • fMRI can detect developmental shifts in brain activation for semantic language.
    • Language processing shows increasing lateralization in the developing brain.
    • Age-related changes in brain organization for language are evident in childhood.