Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Normal fMRI brain activation patterns in children performing a verb generation task.

S K Holland1, E Plante, A Weber Byars

  • 1Children's Hospital Research Foundation, University of Cincinnati, Cincinnati, Ohio, USA.

Neuroimage
|September 14, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diffusion imaging markers of bipolar versus general psychopathology risk in youth at-risk.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2018
Same author

Reward-related neural activity and structure predict future substance use in dysregulated youth.

Psychological medicine·2016
Same author

Predicting clinical outcome from reward circuitry function and white matter structure in behaviorally and emotionally dysregulated youth.

Molecular psychiatry·2016
Same author

Age at stroke determines post-stroke language lateralization.

Restorative neurology and neuroscience·2014
Same author

Success rates for functional MR imaging in children.

AJNR. American journal of neuroradiology·2014
Same author

Behavioral and emotional dysregulation trajectories marked by prefrontal-amygdala function in symptomatic youth.

Psychological medicine·2014
Same journal

Brain-Inspired Large Model Mindreading.

NeuroImage·2026
Same journal

Light on Broken Networks: Resting-State fNIRS as a Tool for Connectivity Mapping.

NeuroImage·2026
Same journal

Criticism-Evoked Rumination Is Linked to Dynamic adjustments of the Left Superficial Amygdala in Adolescents.

NeuroImage·2026
Same journal

GeNED.ar cohort: Neuroimaging Resource for Aging Studies in an Admixed Population from Argentina.

NeuroImage·2026
Same journal

DTI-ALPS index correlates with poor neuromodulation outcomes of bilateral STN-DBS in Parkinson's disease patients: a prospective cohort study.

NeuroImage·2026
Same journal

Decoding neuronal criticality firing patterns for large brain based EEG models.

NeuroImage·2026
See all related articles

Brain imaging in children reveals that language processing becomes more specialized in the left hemisphere as they age. This developmental shift in brain activation patterns was observed using functional magnetic resonance imaging.

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Cognitive Science

Background:

  • Limited understanding of brain-language relationships during childhood development.
  • Established knowledge of adult brain-language networks.

Purpose of the Study:

  • Investigate developmental changes in brain activation for semantic language tasks in children.
  • Examine the relationship between age and hemispheric lateralization of language function.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) at 3 Tesla.
  • Word fluency paradigm administered to 17 children (ages 7-18).
  • Analysis of brain activation patterns and hemispheric dominance.

Main Results:

Related Experiment Videos

  • Brain activation regions in children replicated adult findings.
  • A significant association between age and hemispheric lateralization was observed.
  • The degree of left hemisphere dominance for language tasks increased with age.

    • Conclusions:

    • fMRI can detect developmental shifts in brain activation for semantic language.
    • Language processing shows increasing lateralization in the developing brain.
    • Age-related changes in brain organization for language are evident in childhood.