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Related Concept Videos

Golgi Apparatus01:49

Golgi Apparatus

As they leave the Endoplasmic Reticulum (ER), properly folded and assembled proteins are selectively packaged into vesicles. These vesicles are transported by microtubule-based motor proteins and fuse together to form vesicular tubular clusters, subsequently arriving at the Golgi apparatus, a eukaryotic endomembrane organelle that often has a distinctive ribbon-like appearance.The Golgi apparatus is a major sorting and dispatch station for the products of the ER. Newly arriving vesicles enter...
Golgi Apparatus01:09

Golgi Apparatus

Properly folded and assembled proteins are selectively packaged into vesicles that exit the ER. Motor proteins transport these vesicles to the Golgi apparatus for adding modifications that make these proteins functional at their destination.
The Golgi apparatus is a eukaryotic organelle that has a distinctive ribbon-like appearance. It is a primary sorting and dispatch station for cargo arriving from the ER. Newly arriving vesicles enter the cis face of the Golgi, closest to the ER, and are...
Golgi Matrix Proteins01:12

Golgi Matrix Proteins

Golgi matrix proteins are a group of highly dynamic proteins that maintain the stacked structure of Golgi. These proteins adapt to rapid morphological changes of the Golgi during the cell cycle. During cell division, mild proteolysis removes these connections resulting in Golgi unstacking. In The daughter cells, these proteins help reassemble the unstacked Golgi.
One of the first identified Golgi matrix proteins was GM130, a rod-like protein located in the cis-Golgi. Subsequently, many Golgi...
Distribution of Cytoplasmic Content02:33

Distribution of Cytoplasmic Content

Cytokinesis segregates a cell’s chromosomes and organelles into its daughter cells. Organelles divide and grow prior to cell division but cannot be synthesized de novo; therefore, cells must receive at least one copy of each organelle to survive. Currently, many of the details of how the organelles are distributed are not yet fully elucidated.
Distribution of cytoplasmic determinants
The cytoplasm contains various organelles, as well as salts, proteins, and water. The distribution of small...
Transport Across the Golgi01:26

Transport Across the Golgi

While it is unclear how molecules move between adjacent Golgi cisternae, it is apparent that the molecules move from cis- cisterna, the entry face, to the trans- cisterna, the exit face. Experiments initially suggested vesicles that bud from one cisterna and fuse with the next cisterna to transport proteins between the cisternae. This vesicular transport model describes the Golgi apparatus as a relatively static structure with a unique enzyme composition in each cisterna. Molecules are...
Golgi Apparatus01:09

Golgi Apparatus

Properly folded and assembled proteins are selectively packaged into vesicles that exit the ER. Motor proteins transport these vesicles to the Golgi apparatus for adding modifications that make these proteins functional at their destination.
The Golgi apparatus is a eukaryotic organelle that has a distinctive ribbon-like appearance. It is a primary sorting and dispatch station for cargo arriving from the ER. Newly arriving vesicles enter the cis face of the Golgi, closest to the ER, and are...

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Related Experiment Video

Updated: Jul 8, 2026

Assessment of Hippocampal Dendritic Complexity in Aged Mice Using the Golgi-Cox Method
09:44

Assessment of Hippocampal Dendritic Complexity in Aged Mice Using the Golgi-Cox Method

Published on: June 22, 2017

Deconstructing Golgi inheritance.

O W Rossanese1, B S Glick

  • 1Department of Molecular Genetics and Cell Biology, The University of Chicago, 920 East 58th Street, Chicago, IL 60637, USA.

Traffic (Copenhagen, Denmark)
|September 14, 2001
PubMed
Summary
This summary is machine-generated.

Eukaryotic cells inherit the Golgi apparatus through diverse strategies, involving fragmentation and endoplasmic reticulum redistribution during mitosis. Common mechanisms across eukaryotes ensure Golgi inheritance in daughter cells.

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Quantitative Localization of a Golgi Protein by Imaging Its Center of Fluorescence Mass
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Quantitative Localization of a Golgi Protein by Imaging Its Center of Fluorescence Mass

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High-throughput Screening for Protein-based Inheritance in S. cerevisiae
08:12

High-throughput Screening for Protein-based Inheritance in S. cerevisiae

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Related Experiment Videos

Last Updated: Jul 8, 2026

Assessment of Hippocampal Dendritic Complexity in Aged Mice Using the Golgi-Cox Method
09:44

Assessment of Hippocampal Dendritic Complexity in Aged Mice Using the Golgi-Cox Method

Published on: June 22, 2017

Quantitative Localization of a Golgi Protein by Imaging Its Center of Fluorescence Mass
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Quantitative Localization of a Golgi Protein by Imaging Its Center of Fluorescence Mass

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High-throughput Screening for Protein-based Inheritance in S. cerevisiae
08:12

High-throughput Screening for Protein-based Inheritance in S. cerevisiae

Published on: August 8, 2017

Area of Science:

  • Cell Biology
  • Molecular Biology
  • Genetics

Background:

  • Eukaryotic cells employ various strategies for Golgi apparatus inheritance.
  • Vertebrate mitosis involves dramatic Golgi reorganization, including fragmentation and redistribution to the endoplasmic reticulum.
  • The functions of proteins involved in vertebrate Golgi inheritance are not fully understood.

Purpose of the Study:

  • To compare Golgi inheritance mechanisms between vertebrates and other eukaryotes.
  • To elucidate common strategies for Golgi apparatus partitioning or de novo formation during cell division.

Main Methods:

  • Comparative analysis of Golgi inheritance in different eukaryotic cell types.
  • Observation of Golgi structure dynamics during mitosis.
  • Investigation of membrane traffic regulation during cell division.

Main Results:

  • Golgi stacks undergo fission early in mitosis across many cell types.
  • Some cells show further Golgi breakdown due to inhibited membrane traffic during mitosis.
  • Common mechanisms for Golgi inheritance identified across eukaryotes.

Conclusions:

  • Golgi inheritance in eukaryotes involves partitioning existing Golgi elements or de novo formation from the endoplasmic reticulum.
  • These pathways, or a combination, ensure proper Golgi distribution to daughter cells.
  • Understanding these mechanisms is crucial for cell division fidelity.