Related Experiment Video
Updated: Jul 20, 2026

Intraoperative Ultrasound in Spinal Surgery
Published on: August 17, 2022
May 2001: 32 year old female with dural mass encircling cervical spinal cord
P J McCarthy1, W P Arend, B K Kleinschmidt-DeMasters
1Department of Pathology, University of Colorado Health Sciences Center, Denver, USA.
Abstract:
The May COM. A 32-year-old woman with a history of previous mastoid surgery presented with bilateral extremity weakness and ambulatory instability. MRI revealed a dural-based mass completely encircling the upper cervical spinal cord. Workup was significant for an abnormally elevated c-ANCA, positive at a dilution of 1:128. A portion of the lesion was removed by a posterior surgical approach to decompress the cervical cord. Histologic examination of the dura showed a dense granulomatous infiltrate with vasculitis and giant cells; coupled with the positive c-ANCA, the process was felt to be most consistent with Wegener's granulomatosis. Wegener's granulomatosis infrequently involves the dura or meninges and has not previously been reported to affect dura of the cervical cord. Symptomatic improvement followed surgical decompression and high-dose corticosteroid therapy, with resultant resolution of an elevated c-ANCA titer.
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