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Nuclear PtdIns(4,5)P2 assembles in a mitotically regulated particle involved in pre-mRNA splicing

S L Osborne1, C L Thomas, S Gschmeissner

  • 1Molecular Neuropathobiology Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK.

Journal of Cell Science
|September 18, 2001
PubMed
Summary

Nuclear phosphatidylinositol(4,5)-bisphosphate (PtdIns(4,5)P2) associates with nuclear bodies involved in transcription and splicing. PtdIns(4,5)P2 is crucial for pre-mRNA processing, highlighting its essential nuclear role.

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