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Amniotic membrane transplantation for ocular surface reconstruction
P Prabhasawat1, P Kosrirukvongs, W Booranapong
1Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
|September 19, 2001
Summary
Amniotic membrane transplantation effectively treats various ocular surface conditions, promoting healing and reducing scarring. This procedure offers a viable solution for complex corneal and conjunctival reconstruction challenges.
Area of Science:
- Ophthalmology
- Regenerative Medicine
- Tissue Engineering
Background:
- Ocular surface reconstruction presents significant challenges.
- Amniotic membrane transplantation (AMT) is a promising therapeutic option.
Observation:
- This study evaluated AMT efficacy in 140 eyes across diverse indications.
- Indications included limbal stem cell deficiency, bullous keratopathy, and conjunctival tumors.
Findings:
- Overall success and partial success rates reached 93.6% (131/140 eyes).
- Corneal and conjunctival groups showed high efficacy, with success rates of 80.6% and 71.2%, respectively.
Implications:
- AMT is effective for challenging ocular surface reconstructions.
- The procedure aids epithelial healing, reduces inflammation, and minimizes scarring.