[The pyramidal tract: new pathways]
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Updated: Oct 4, 2026

Unilateral Pyramidotomy of the Corticospinal Tract in Rats for Assessment of Neuroplasticity-inducing Therapies
Published on: December 15, 2014
M L Cuadrado1, J A Arias, M A Palomar
1Universidad Rey Juan Carlos, Madrid, 28922, España. m.cuadrado@cs.urjc.es
Objective:
To review some anatomofunctional aspects of the pyramidal tract which are relevant in clinical practice, especially the newer concepts.
Development:
a) Although the motor function is best known, the pyramidal tract also has sensory functions, modulating the transmission of impulses in the spinal cord. In fact, motor function is a recent acquisition on the evolutionary scale. b) Other descending pathways, such as the cortico reticulospinal path, participate in voluntary movements. However, the pyramidal pathway is necessary for fine movements of the hand. c) Most of the pyramidal fibres control movements of the contralateral side of the body, but there are a few fibres which do not cross to the other side and play a part in ipsilateral body movements. These fibres seem to contribute to motor recovery following a brain lesion. d) Classically it is recognized that the motor cortex and pyramidal fibres follow a somatotopical distribution. Nevertheless territories corresponding to different parts of the body are superimposed to a considerable extent and may be modified on very diverse occasions. e) Experimentally it has been proved that a circumscribed lesion of the pyramidal pathway does not cause hyper reflexia or spasticity. The hyper reflexia and spasticity habitually seen in patients with pyramidal syndrome is due to lesions of other descending pathways.
Conclusion:
The pyramidal tract is anatomically and functionally related to other nerve structures and its activity is therefore integrated within the nervous system.
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