Related Experiment Video
Updated: Aug 15, 2026

A Friction Testing-Bioreactor Device for Study of Synovial Joint Biomechanics, Mechanobiology, and Physical Regulation
Published on: June 2, 2022
The history of synoviorthesis in haemophilia
1Leni & Peter W. May Department of Orthopedic Surgery, Mount Sinai Hospital, New York, USA. marvandmax@aol.com
The history of synoviorthesis and recent studies have shown that it is a safe procedure and that the results are similar to those seen following open surgical and arthroscopic synovectomy. If the safety of this procedure is definitively proven in long-term studies it will become the procedure of choice for treatment of recurrent haemarthroses and synovitis. That is, until the time when the haematologists and geneticists eliminate the need for orthopaedic intervention in the care of persons with haemophilia.
The history of synoviorthesis and recent studies have shown that it is a safe procedure and that the results are similar to those seen following open surgical and arthroscopic synovectomy. If the safety of this procedure is definitively proven in long-term studies it will become the procedure of choice for treatment of recurrent haemarthroses and synovitis. That is, until the time when the haematologists and geneticists eliminate the need for orthopaedic intervention in the care of persons with haemophilia.
Related Concept Videos
Development of the Limb Synovial Joints
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
Introduction to Hemostasis
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...
Extrinsic and Intrinsic Pathways of Hemostasis
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which forms a...
Clot Retraction and Fibrinolysis
Disorders of Hemostasis
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Nephrotic Syndrome I : Introduction

